By P. Dawson PhD, MRCP, FRCR (auth.), P. Dawson, W. Clauss (eds.)
For all that new non-X-ray applied sciences reminiscent of MR and ultrasound and its a variety of manifestations have made an incredible influence lately at the perform of clinical imaging, using X-rays and X-ray contrast-enhancing brokers has retained an enormous place on the middle of the method. certainly, with its common requisites for top overall dose regimes, CT has elevated using distinction brokers. Even helical/spiral CT which, it was once in the beginning argued, may still lessen distinction in addition to radiation quite a bit, may very well require simply as a lot or extra of either a result of power it deals for multi-phase scanning.
Iodinated intravascular X-ray distinction brokers, particularly the extra lately built non-ionic brokers, proceed hence to play a pivotal position in scientific imaging.
those succinct and authoritative articles, initially showing within the magazine Advances in X-ray Contrast, diversity sufficiently generally for his or her compilation during this quantity to be thought of a mini-textbook at the water-soluble iodinated X-ray distinction brokers and their functions. every one is written by means of an stated and skilled specialist within the box. They usefully disguise the developmental background of the brokers; outlined possibility elements, techniques to prophylaxis and, finally, of the therapy of difficult reactions; the fascinating topic of intended behind schedule reactions to distinction brokers; the real organ-specific toxicities, cardiac toxicity, neurotoxicity and nephrotoxicity and high-dose toxicity as encountered in complicated strategies; the occasionally precise conditions and coffee severe stipulations to which distinction brokers might be uncovered in Interventional Radiology; the targeted, in different methods, case of paediatric radiology; the debatable topic of thromboembolic phenomena in medical angiography; and the fitting position of distinction brokers. As regards the practicalities of distinction management regimes and imaging protocols it truly is simply within the zone of CT that there's debate and controversy, and articles are integrated which disguise CT of the liver, spleen and pancreas, and protocols for the recent spiral/helical expertise or even for the less greatly on hand electron-beam CT expertise visualization. Pulmonary embolus analysis and protocols for distinction management with this know-how also are discussed.
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Additional info for Advances in X-Ray Contrast: Collected Papers
The authors were able to show that the incidence of late reactions fell as age increased. Because they had a large number of patients they were able to analyse risk factors for patients having intravenous low osmolar non-ionic contrast. They found that in the acute group the statistically significant risk factors were allergy, drug allergy and previous reaction to contrast medium; the risk factors for late reactions were female sex, allergy, drug allergy and the presence of other diseases, and most importantly previous reaction to contrast medium.
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Dawson P, Hewitt MR, Mackie U, Machin SJ, Amin S, Bradshaw A. Contrast, coagUlation and fibrinolysis. Invest Radiol. 1986; 21: 248-252. 12. Stormorken H, Skalpe 10, Testart Me. Effect of various contrast media on coagulation, fibrinolysis and platelet function: an in vitro and in vivo study. Invest Radiol. 1986; 21: 348-354. 13. McAfee JG. Survey of complications of abdominal arteriography. Radiology. 1957; 68: 825-827. 14. Adams DF, Fraser DB, Abrams HC. The complication of coronary arteriography.